Genetics of Ageing

Ageing happens because of the pleiotropic impacts of genes that determine various processes. Genes that impact longevity are associated with nutrient sensing and stress response. Telomere shortening prompts cell development arrest and apoptosis. Genes associated with ageing or longevity have different functions in cells, particularly roles in pressure reaction and control of metabolism process. Human genetic disorders like Hutchinson-Gilford Progeria and Werner's syndrome and give clues of information about cellular ageing in humans and recommend that ageing associates with elevated mutation rates, changes in gene expression, and arrest of cell division. 

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